Author: Daniel C. Isaksen Author's e-mail address: isaksen@math.wayne.edu Author's mailing address: Department of Mathematics \\ Wayne State University \\ Detroit, MI 48202 Included ps or eps files: None AMS classification number: 55P60, 55N10 (Primary); 18G55, 55U35 (Secondary) Abstract: For every ring R, we present a pair of model structures on the category of pro-spaces. In the first, the weak equivalences are detected by cohomology with coefficients in R. In the second, the weak equivalences are detected by cohomology with coefficients in all R-modules (or equivalently by pro-homology with coefficients in R). In the second model structure, fibrant replacement is essentially just the Bousfield-Kan R-tower. When R = Z/p, the first homotopy category is equivalent to a homotopy theory defined by Morel but has some convenient categorical advantages.