Le localisateur fondamental minimal Denis-Charles Cisinski AMS Classification numbers 55U40 Institut de Mathématiques de Jussieu Université Paris 7 Case 7012 2 place Jussieu 75251 Paris cedex 05 France E-mail: cisinski@math.jussieu.fr Abstract Basic localizors were introduced by Grothendieck in Pursuing Stacks. These are classes of arrows in the category Cat of small categories satisfying nice properties of descent (like Quillen's theorem A).For example, every cohomology theory defines a basic localizor. In particular, classical weak equivalences (i.e. those induced from the simplicial weak equivalences from th nerve functor) form a basic localizor. In this paper, we show Grothendieck's conjecture that Cat's usual weak equivalences are the smallest basic localizor. This gives in particular a combinatorial/algebraic way to define classical homotopy theory.